Relationship between atrophy and beta-amyloid deposition in Alzheimer disease.

Elucidating the role of aggregated beta-amyloid in relation to gray matter atrophy is crucial to the understanding of the pathological mechanisms of Alzheimer disease and for the development of therapeutic trials. The present study aims to assess this relationship.

• Publication date: Mar 2010
• Journal: Annals of neurology
• Publication date: Chételat G, Villemagne VL, Bourgeat P, Pike KE, Jones G, Ames D, Ellis KA, Szoeke C, Martins RN, O'Keefe GJ, Salvado O, Masters CL, Rowe CC,
• ISSN: 1531-8249