Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer’s disease and semantic dementia.

Hippocampal atrophy is a well-known feature of Alzheimer's disease (AD), but sensitivity and specificity of hippocampal volumetry are limited. Neuropathological studies have shown that hippocampal subfields are differentially vulnerable to AD; hippocampal subfield volumetry may thus prove to be more accurate than global hippocampal volumetry to detect AD.

• Publication date: 2013
• Journal: NeuroImage. Clinical
• Publication date: La Joie R, Perrotin A, de La Sayette V, Egret S, Doeuvre L, Belliard S, Eustache F, Desgranges B, Chételat G
• ISSN: 2213-1582