Brain and cognitive correlates of sleep fragmentation in elderly subjects with and without cognitive deficits.

Sleep disturbances are increasingly recognized as a risk factor for Alzheimer's disease. However, no study has assessed the relationships between objective sleep fragmentation (SF) and brain and cognitive integrity across different cognitive stages, from cognitively unimpaired elderly subjects to patients with subjective cognitive decline and/or mild cognitive impairment.

• Publication date: Dec 2019
• Journal: Alzheimer's & dementia (Amsterdam, Netherlands)
• Publication date: André C, Tomadesso C, de Flores R, Branger P, Rehel S, Mézenge F, Landeau B, Sayette V, Eustache F, Chételat G, Rauchs G
• ISSN: 2352-8729